The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesWB: Use at a concentration of 0.5 - 2.0 µg/ml. Detects a band of approximately 80 kDa (predicted molecular weight: 82 kDa).
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionMay be involved in the regulation of gene expression by covalent modification of histone proteins. Isoform Long is a corepressor of estrogen receptor (ER). Isoform Short binds to ER and sequesters it in the cytoplasm and enhances non-genomic responses of ER.
Tissue specificityWidely expressed. High expression in brain, ovaries, adrenal glands and virgin mammary glands. Higher in tumors than in adjacent normal tissue from the same individual.