Overview

  • Product nameAnti-MTA1 antibody
    See all MTA1 primary antibodies
  • Description
    Rabbit polyclonal to MTA1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse, Cow, Dog, Ferret, Rhesus monkey, Gorilla, Orangutan, Elephant
  • Immunogen

    Synthetic peptide corresponding to a region within residues 400 and 450 of human MTA1 (SwissProt entry Q13330).

  • Positive control
    • Human stomach adenocarcinoma; human lung non small cell carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab84136 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Antigen retrieval is not essential but may optimise staining. The use of citrate buffer will enhance staining.

Target

  • FunctionMay be involved in the regulation of gene expression by covalent modification of histone proteins. Isoform Long is a corepressor of estrogen receptor (ER). Isoform Short binds to ER and sequesters it in the cytoplasm and enhances non-genomic responses of ER.
  • Tissue specificityWidely expressed. High expression in brain, ovaries, adrenal glands and virgin mammary glands. Higher in tumors than in adjacent normal tissue from the same individual.
  • Sequence similaritiesContains 1 BAH domain.
    Contains 1 ELM2 domain.
    Contains 1 GATA-type zinc finger.
    Contains 1 SANT domain.
  • Developmental stageHighly expressed in metastatic cells.
  • DomainIsoform Short contains a Leu-Arg-Ile-Leu-Leu motif (ER binding motif).
  • Cellular localizationCytoplasm and Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Metastasis associated 1 antibody
    • Metastasis associated gene 1 antibody
    • Metastasis associated gene 1 protein antibody
    • Metastasis associated protein antibody
    • Metastasis associated protein MTA 1 antibody
    • Metastasis associated protein MTA1 antibody
    • Metastasis-associated protein MTA1 antibody
    • MTA 1 antibody
    • MTA1 antibody
    • MTA1_HUMAN antibody
    see all

Anti-MTA1 antibody images

  • ab84136, at a 1/100 dilution, staining MTA1 in formalin fixed, paraffin embedded human stomach adenocarcinoma tissue by Immunohistochemistry. Detection: DAB staining.
  • ab84136, at a 1/100 dilution, staining MTA1 in formalin fixed, paraffin embedded human lung non small cell carcinoma tissue by Immunohistochemistry. Detection: DAB staining.

References for Anti-MTA1 antibody (ab84136)

This product has been referenced in:
  • Agboola AO  et al. Clinicopathological and molecular significance of Sumolyation marker (ubiquitin conjugating enzyme 9 (UBC9)) expression in breast cancer of black women. Pathol Res Pract N/A:N/A (2013). IHC-P ; Human . Read more (PubMed: 24176171) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab84136.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"