The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Antigen retrieval is not essential but may optimise staining. The use of citrate buffer will enhance staining.
FunctionMay be involved in the regulation of gene expression by covalent modification of histone proteins. Isoform Long is a corepressor of estrogen receptor (ER). Isoform Short binds to ER and sequesters it in the cytoplasm and enhances non-genomic responses of ER.
Tissue specificityWidely expressed. High expression in brain, ovaries, adrenal glands and virgin mammary glands. Higher in tumors than in adjacent normal tissue from the same individual.
ab84136, at a 1/100 dilution, staining MTA1 in formalin fixed, paraffin embedded human lung non small cell carcinoma tissue by Immunohistochemistry. Detection: DAB staining.
References for Anti-MTA1 antibody (ab84136)
This product has been referenced in:
Agboola AO et al. Clinicopathological and molecular significance of Sumolyation marker (ubiquitin conjugating enzyme 9 (UBC9)) expression in breast cancer of black women. Pathol Res PractN/A:N/A (2013).
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