Overview

  • Product name
    MTBP peptide

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab6235 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Additional notes
    Stable for one year.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • hMTBP
    • MDM 2 binding protein
    • MDM 2 BP
    • MDM2 (mouse double minute 2) binding protein
    • MDM2 (mouse double minute 2) binding protein 104kD
    • MDM2 binding protein
    • MDM2 BP
    • Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein
    • Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa
    • Mdm2 transformed 3T3 cell double minute 2 p53 binding protein binding protein
    • Mdm2-binding protein
    • MDM2BP
    • Mouse double minute 2 homolog binding protein
    • MTBP
    • MTBP_HUMAN
    see all
  • Function
    Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.
  • Sequence similarities
    Belongs to the MTBP family.
  • Information by UniProt

References

ab6235 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab6235.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up