Overview

  • Product name
  • Description
    Rabbit polyclonal to MTHFS
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 57-203 of Human MTHFS (AAH19921).

  • Positive control
    • A549 and HepG2 whole cell lysates; AGS xenograft tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab104009 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 23 kDa.
IHC-P 1/100 - 1/500. (Suggested antigen retrieval using heat mediated 10mM Citrate buffer or Tris-EDTA buffer (PH8.0)).

Target

  • Function
    Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate.
  • Sequence similarities
    Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • 10-methenyl-tetrahydrofolate synthetase antibody
    • 5 10 methenyl tetrahydrofolate synthetase antibody
    • 5 antibody
    • 5 formyltetrahydrofolate cyclo ligase antibody
    • 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) antibody
    • 5-formyltetrahydrofolate cyclo-ligase antibody
    • FLJ30410 antibody
    • HsT19268 antibody
    • Methenyl THF synthetase antibody
    • Methenyl-THF synthetase antibody
    • MTHFS antibody
    • MTHFS_HUMAN antibody
    see all

Images

  • All lanes : Anti-MTHFS antibody (ab104009) at 1/1000 dilution

    Lane 1 : A549 whole cell lysate
    Lane 2 : HepG2 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 23 kDa
  • ab104009 at 1/100 dilution staining MTHFS in AGS xenograft by Immunohistochemistry, Paraffin-embedded tissue.

References

ab104009 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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