• Product nameAnti-MTMR2 antibody
    See all MTMR2 primary antibodies
  • Description
    Rabbit polyclonal to MTMR2
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Cow, Zebrafish
  • Immunogen

    Recombinant fragment, corresponding to a sequence within amino acids 221-497 of Human MTMR2 (AAH52990).

  • Positive control
    • HeLa and Raji cell lysates; HepG2 whole cell lysates; CL1-0 xenograft tissue.



Our Abpromise guarantee covers the use of ab96583 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 73 kDa.
IHC-P 1/100 - 1/500.


  • FunctionPhosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate.
  • Involvement in diseaseDefects in MTMR2 are the cause of Charcot-Marie-Tooth disease type 4B1 (CMT4B1) [MIM:601382]. CMT4B1 is a recessive, severe form of Charcot-Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathy and primary peripheral axonal neuropathy. Demyelinating CMT neuropathies are characterized by severely reduced nerve conduction velocities (less than 38 m/sec), segmental demyelination and remyelination with onion bulb formations on nerve biopsy, slowly progressive distal muscle atrophy and weakness, absent deep tendon reflexes, and hollow feet. By convention, autosomal recessive forms of demyelinating Charcot-Marie-Tooth disease are designated CMT4.
  • Sequence similaritiesBelongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
    Contains 1 GRAM domain.
    Contains 1 myotubularin phosphatase domain.
  • DomainThe coiled-coil domain mediates interaction with SBF2.
  • Cellular localizationCytoplasm. Membrane. Partly associated with membranes.
  • Information by UniProt
  • Database links
  • Alternative names
    • CMT4B antibody
    • CMT4B1 antibody
    • KIAA1073 antibody
    • MTMR2 antibody
    • MTMR2_HUMAN antibody
    • Myotubularin related protein 2 antibody
    • Myotubularin-related protein 2 antibody
    • OTTHUMP00000204445 antibody
    • OTTHUMP00000204446 antibody
    • OTTHUMP00000204447 antibody
    • OTTHUMP00000204448 antibody
    • Phosphatidylinositol 3 phosphate phosphatase antibody
    • Phosphatidylinositol 3,5 bisphosphate 3 phosphatase antibody
    see all

Anti-MTMR2 antibody images

  • Anti-MTMR2 antibody (ab96583) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 73 kDa
  • ab96583 at 1/100 dilution staining MTMR2 in CL1-0 xenograft by Immunohistochemistry, Paraffin-embedded tissue.

References for Anti-MTMR2 antibody (ab96583)

ab96583 has not yet been referenced specifically in any publications.

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Thank you for contacting us and for your interest in our products. I am sorry to confirm that as far as we are aware, ab96583 MTMR2 antibody has never been tested in mouse. All tested and guaranteed applications and species are specified on our data...

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