Overview

  • Product name
  • Description
    Rabbit polyclonal to MTMR3
  • Tested applications
    Suitable for: IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence, corresponding to amino acids 636-740 of Human MTMR3.

  • Positive control
    • Human testis tissue; A431 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab122213 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml. Fixation/Permeabilization: PFA/Triton X-100

Target

  • Function
    Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. May also dephosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues.
  • Sequence similarities
    Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
    Contains 1 FYVE-type zinc finger.
    Contains 1 myotubularin phosphatase domain.
  • Cellular localization
    Cytoplasm. Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • FYVE domain-containing dual specificity protein phosphatase 1 antibody
    • FYVE-DSP1 antibody
    • MTMR3 antibody
    • MTMR3_HUMAN antibody
    • Myotubularin-related protein 3 antibody
    • Zinc finger FYVE domain-containing protein 10 antibody
    see all

Images

  • ab122213 at 1/1000 dilution staining MTMR3 in Paraffin-embedded Human Testis tissue by Immunohistochemistry.
  • ab122213 at 4 µg/ml staining MTMR3 (green) in PFA-fixed/Triton-permeabilized Human A431 cells by Immunofluorescence.

References

ab122213 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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