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Function
Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3).
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Tissue specificity
Expressed in brain, heart, kidney, spleen, liver, colon, testis, muscle, placenta, thyroid gland, pancreas, ovary, prostate, skin, peripheral blood, and bone marrow.
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Sequence similarities
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
Contains 1 FYVE-type zinc finger.
Contains 1 myotubularin phosphatase domain.
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Developmental stage
Expressed in fetal brain and fetal liver.
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Cellular localization
Cytoplasm. Membrane. Localized to perinuclear region.
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Information by UniProt
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Database links
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Alternative names
- FYVE domain containing dual specificity protein phosphatase 2 antibody
- FYVE domain-containing dual specificity protein phosphatase 2 antibody
- FYVE domain-containing dual specificity protein phosphatase FYVE DSP2 antibody
- FYVE-DSP2 antibody
- Mtmr4 antibody
- MTMR4_HUMAN antibody
- Myotubularin related protein 4 antibody
- Myotubularin-related protein 4 antibody
- ZFYVE11 antibody
- zinc finger FYVE domain containing 11 antibody
- Zinc finger FYVE domain containing protein 11 antibody
- Zinc finger FYVE domain-containing protein 11 antibody
see all