Overview

  • Product name
  • Description
    Rabbit polyclonal to MTO1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide from within residues: STVYAESVIL TTGTFLRGMI VIGLETHPAG RLGDQPSIGL AQTLEKLGFV, corresponding to internal sequence amino acids 182-231 of Human MTO1 (NP_001116698).

  • Positive control
    • Human fetal muscle lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab105066 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 80 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Relevance
    The Protein MTO1 homolog is involved in the 5 carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. It is ubiquitously expressed in various tissues, but with a markedly elevated expression in tissues of high metabolic rates including cochlea. The protein belongs to the gidA family.
  • Cellular localization
    Mitochondrial
  • Database links
  • Alternative names
    • mitochondrial MTO1 3 antibody
    • mitochondrial translation optimization 1 homolog antibody
    • protein MTO1 homolog, mitochondrial precursor antibody

Anti-MTO1 antibody images

  • Anti-MTO1 antibody (ab105066) at 1 µg/ml + Human fetal muscle lysate at 10 µg

    Predicted band size : 80 kDa

References for Anti-MTO1 antibody (ab105066)

This product has been referenced in:
  • Becker L  et al. MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy. PLoS One 9:e114918 (2014). WB . Read more (PubMed: 25506927) »

See 1 Publication for this product

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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