Overview

  • Product name
  • Description
    Rabbit polyclonal to MTUS1
  • Tested applications
    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide coresponding to a region between amino acids 450-500 of Human MTUS1 (NP_001001924.1)

  • Positive control
    • HeLa cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab113979 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-5 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Relevance
      Multiple alternatively spliced transcript variants encoding different isoforms have been found for the MTUS1 (Mitochondrial tumor suppressor 1) gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and cooperates with the angiotension II (AT2) receptor (AGTR2) to inhibit ERK2 activation and cell proliferation. MTUS1 polypeptides are identical in their carboxy-terminal region carrying four coiled-coil domains. In their amino-terminal portion, MTUS1 polypeptides exhibit distinct motifs for localisation in the cytosol, nucleus or cell membrane, suggesting that MTUS1 gene products may be involved in a variety of intracellular functions in an AT2-dependent and independent manner.
    • Cellular localization
      Cell Membrane, Golgi Apparatus, Mitochondrial and Nuclear. Note=In neurons, translocates into the nucleus after treatment with angiotensin-II.
    • Database links
    • Alternative names
      • AGTR2-interacting protein antibody
      • Angiotensin II type 2 receptor interacting protein antibody
      • AT2 receptor interacting protein antibody
      • AT2 receptor-binding protein antibody
      • AT2R binding protein antibody
      • ATBP antibody
      • ATIP antibody
      • ATIP1 antibody
      • DKFZp586D1519 antibody
      • DKFZp686F20243 antibody
      • Erythroid differentiation related antibody
      • FLJ14295 antibody
      • GK 1 antibody
      • GK1 antibody
      • KIAA1288 antibody
      • Microtubule associated tumor suppressor 1 antibody
      • Mitochondrial tumor suppressor 1 antibody
      • Mitochondrial tumor suppressor gene 1 antibody
      • MP 44 antibody
      • MP44 antibody
      • MTSG 1 antibody
      • MTSG1 antibody
      • MTUS 1 antibody
      • Transcription factor MTSG1 antibody
      see all

    Images

    • ab113979, used for IP at 3 µg/mg lysate, staining MTUS1 in HeLa whole cell lysate (1 mg for IP, 20% of IP loaded).

      Detection: Chemiluminescence with an exposure time of 30 seconds.

    References

    ab113979 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab113979.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up