Overview

  • Product nameAnti-MUC17 antibody
  • Description
    Rabbit polyclonal to MUC17
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence, corresponding to amino acids 4122-4262 of Human MUC17.

  • Positive control
    • Human small intestine tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab122184 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionProbably plays a role in maintaining homeostasis on mucosal surfaces.
  • Tissue specificityExpressed almost exclusively in the intestine. Expression is especially high in both the duodenum and transverse colon. Expressed in mature absorptive cells of the small intestinal villi. No expression is detected in goblet cells. Highly expressed in pancreatic adenocarcinoma tissue (at protein level). Expression is not detectable in normal pancreas, in pancreatitis or in cell lines derived from other cancers.
  • Sequence similaritiesContains 1 EGF-like domain.
    Contains 1 SEA domain.
  • Post-translational
    modifications
    Probably cleaved within the SEA domain.
    N-glycosylated. Contains high mannose and complex-type glycans. The forms containing the complex type glycans localize to the cell surface. Not O-glycosylated.
  • Cellular localizationCell membrane and Secreted. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Membrane mucin MUC17 antibody
    • MUC-17 antibody
    • MUC-3 antibody
    • MUC17 antibody
    • MUC17_HUMAN antibody
    • Mucin 17, cell surface associated antibody
    • Mucin-17 antibody
    • Secreted mucin MUC17 antibody
    • Small intestinal mucin MUC3 antibody
    • Small intestinal mucin-3 antibody
    see all

Anti-MUC17 antibody images

  • ab122184 at 1/20 dilution staining MUC17 in Paraffin-embedded Human Small intestine tissue by Immunohistochemistry.

References for Anti-MUC17 antibody (ab122184)

ab122184 has not yet been referenced specifically in any publications.

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