Anti-Muc19 antibody (ab121014)
Key features and details
- Goat polyclonal to Muc19
- Suitable for: ICC/IF
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-Muc19 antibody -
Description
Goat polyclonal to Muc19 -
Host species
Goat -
Tested applications
Suitable for: ICC/IFmore details -
Species reactivity
Reacts with: Mouse
Predicted to work with: Rat -
Immunogen
Synthetic peptide:
ECKRSVKYNYETFQ
, corresponding to C terminal amino acids 7461-7474 of Mouse Muc19 (NP_997126.2). -
Positive control
- ICC/IF: Mouse sublingual salivary gland cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab121014 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF |
Use a concentration of 1.8 µg/ml.
|
Notes |
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ICC/IF
Use a concentration of 1.8 µg/ml. |
Target
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Function
May function in ocular mucus homeostasis. -
Tissue specificity
Specifically expressed in sublingual salivary glands. Expressed by mucous cells of the submandibular gland and submucosal gland of the trachea. Expression is altered in sld (sublingual gland differentiation arrest) mutants. -
Sequence similarities
Contains 1 CTCK (C-terminal cystine knot-like) domain.
Contains 1 TIL (trypsin inhibitory-like) domain.
Contains 2 VWFC domains.
Contains 3 VWFD domains. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 239611 Mouse
- Entrez Gene: 497227 Rat
- SwissProt: Q6PZE0 Mouse
- Unigene: 46386 Mouse
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Alternative names
- Gel-forming secreted mucin-19 antibody
- MUC-19 antibody
- Muc19 antibody
see all
Images
Protocols
Datasheets and documents
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Datasheet download
References (4)
ab121014 has been referenced in 4 publications.
- Kameyama A et al. Bmi-1 regulates mucin levels and mucin O-glycosylation in the submandibular gland of mice. PLoS One 16:e0245607 (2021). PubMed: 33465144
- Greaney AM et al. Platform Effects on Regeneration by Pulmonary Basal Cells as Evaluated by Single-Cell RNA Sequencing. Cell Rep 30:4250-4265.e6 (2020). PubMed: 32209482
- Praktiknjo SD et al. Tracing tumorigenesis in a solid tumor model at single-cell resolution. Nat Commun 11:991 (2020). PubMed: 32080185
- McBride K et al. Human Metapneumovirus Induces Mucin 19 Which Contributes to Viral Pathogenesis. Pathogens 9:N/A (2020). PubMed: 32899224