Overview

  • Product nameAnti-MUC2 antibody
    See all MUC2 primary antibodies
  • Description
    Rabbit polyclonal to MUC2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within amino acids 4362 and 4426 of Human MUC2 (NP_002448).

  • Positive control
    • H1299, MOLT4 and Raji cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab97386 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 540 kDa.

Target

  • FunctionCoats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.
  • Tissue specificityColon, small intestine, colonic tumors, bronchus, cervix and gall bladder.
  • Sequence similaritiesContains 1 CTCK (C-terminal cystine knot-like) domain.
    Contains 1 TIL (trypsin inhibitory-like) domain.
    Contains 2 VWFC domains.
    Contains 4 VWFD domains.
  • Post-translational
    modifications
    O-glycosylated.
    May undergo proteolytic cleavage in the outer mucus layer of the colon, contributing to the expanded volume and loose nature of this layer which allows for bacterial colonization in contrast to the inner mucus layer which is dense and devoid of bacteria.
    At low pH of 6 and under, undergoes autocatalytic cleavage in vitro in the N-terminal region of the fourth VWD domain. It is likely that this also occurs in vivo and is triggered by the low pH of the late secretory pathway.
  • Cellular localizationSecreted. In the intestine, secreted into the inner and outer mucus layers.
  • Information by UniProt
  • Database links
  • Alternative names
    • Intestinal mucin 2 antibody
    • Intestinal mucin-2 antibody
    • MLP antibody
    • MUC 2 antibody
    • MUC-2 antibody
    • Muc2 antibody
    • MUC2_HUMAN antibody
    • Mucin 2 antibody
    • Mucin 2 intestinal antibody
    • Mucin 2 intestinal/tracheal antibody
    • Mucin 2 oligomeric mucus/gel forming antibody
    • Mucin 2 precursor antibody
    • Mucin 2 tracheal antibody
    • Mucin like protein antibody
    • Mucin-2 antibody
    • Mucin2 antibody
    • SMUC antibody
    see all

Anti-MUC2 antibody images

  • Anti-MUC2 antibody (ab97386) at 1/3000 dilution + Raji whole cell lysate at 30 µg

    Predicted band size : 540 kDa

References for Anti-MUC2 antibody (ab97386)

ab97386 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. Having searched for swine MUC2 sequence from NCBI and SwissProt I have been unable to identify a sequence. I am therefore unable to do a comparison of the human sequence (to which all of our MUC2 antibodies are directed). H...

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