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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer Preservative: None
Constituents: PBS, pH 7.2
Concentration information loading...
Purity Protein A purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 72 kDa.
Function May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.
Tissue specificity Highly expressed in kidney, moderately in placenta, lung, prostate, liver, and digestive system. In the kidney, localized in the proximal tubules but not in the glomerulus or distal tubules. Detected in most of the male urogenital tract epithelia, with the exception of epididymis.
Cellular localization Secreted. Apical cell membrane. Basolateral cell membrane. Cell projection > microvillus membrane.
Information by UniProt
MUC 20 antibody
Anti-MUC20 antibody images
Western blot - MUC20 antibody (ab73043)
All lanes : Anti-MUC20 antibody (ab73043) at 1/500 dilution Lane 1 : MUC20 transfected 293T cell lysate Lane 2 : Non transfected 293T cell lysate Lysates/proteins at 25 µg per lane. Secondary Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution Developed using the ECL technique Predicted band size : 72 kDa Observed band size : 80 kDa ( why is the actual band size different from the predicted?)
References for Anti-MUC20 antibody (ab73043)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"