Overview

  • Product name
    Anti-MUM1 antibody
  • Description
    Mouse polyclonal to MUM1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human protein

  • Positive control
    • FLJ14868-transfected 293T cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab69220 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 79 kDa.

Target

  • Function
    Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
  • Sequence similarities
    Belongs to the MUM1 family.
    Contains 1 PWWP domain.
  • Domain
    The PWWP domain mediates the interaction with nucleosomes.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Nucleus. Recuited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.
  • Information by UniProt
  • Database links
  • Alternative names
    • EXPAND1 antibody
    • FLJ14868 antibody
    • FLJ22283 antibody
    • HSPC211 antibody
    • Melanoma associated antigen (mutated) 1 antibody
    • Melanoma ubiquitous mutated protein antibody
    • MGC131891 antibody
    • MGC163315 antibody
    • MUM 1 antibody
    • MUM-1 antibody
    • MUM1 antibody
    • MUM1_HUMAN antibody
    • Mutated melanoma associated antigen 1 antibody
    • Mutated melanoma-associated antigen 1 antibody
    • Protein expandere antibody
    • PWWP domain containing protein MUM1 antibody
    • PWWP domain-containing protein MUM1 antibody
    see all

Anti-MUM1 antibody images

  • All lanes : Anti-MUM1 antibody (ab69220) at 1/500 dilution

    Lane 1 : MUM1 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

    Predicted band size : 79 kDa
    Observed band size : 90 kDa (why is the actual band size different from the predicted?)

References for Anti-MUM1 antibody (ab69220)

ab69220 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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