Overview

  • Product nameAnti-MURC antibody
    See all MURC primary antibodies
  • Description
    Rabbit polyclonal to MURC
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen, corresponding to amino acids 276-358 (KGKDRTVAEG EECAREMGVD IIARSESLGP ISELYSDELS EPEHEAARPV YPPHEGREIP TPEPLKVTFK SQVKVEDDES LLL) of Human MURC.

  • Positive control
    • Human skeletal muscle tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab121642 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionInduces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway.
  • Sequence similaritiesBelongs to the PTRF/SDPR family.
  • Cellular localizationCytoplasm > myofibril > sarcomere. Cytoplasm. In cardiomyocytes, accumulates in the Z-line of the sarcomere. In vascular smooth muscle cells, detected diffusely throughout the cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • murC antibody
    • MURC_HUMAN antibody
    • Muscle-related coiled-coil protein antibody
    • Muscle-restricted coiled-coil protein antibody

Anti-MURC antibody images

  • ab121642, at 1/1000 dilution, staining MURC in paraffin-embedded Human skeletal muscle tissue, by Immunohistochemistry.

References for Anti-MURC antibody (ab121642)

ab121642 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab121642.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"