Overview

  • Product nameAnti-MURC antibody
    See all MURC primary antibodies
  • Description
    Rabbit polyclonal to MURC
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen, corresponding to amino acids 1-90 (MEHNGSASNA DKIHQNRLSS VTEDEDQDAA LTIVTVLDKV ASIVDSVQAS QKRIEERHRE MENAIKSVQI DLLKLSQSHS NTGHIINKLF) of Human MURC.

  • Positive control
    • Human lymph node tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab121644 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionInduces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway.
  • Sequence similaritiesBelongs to the PTRF/SDPR family.
  • Cellular localizationCytoplasm > myofibril > sarcomere. Cytoplasm. In cardiomyocytes, accumulates in the Z-line of the sarcomere. In vascular smooth muscle cells, detected diffusely throughout the cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • murC antibody
    • MURC_HUMAN antibody
    • Muscle-related coiled-coil protein antibody
    • Muscle-restricted coiled-coil protein antibody

Anti-MURC antibody images

  • ab121644, at 1/60 dilution, staining MURC in paraffin-embedded Human lymph node tissue, by Immunohistochemistry,
  • Immunohistochemical staining of Human skeletal muscle shows distinct membranous positivity using ab121644

References for Anti-MURC antibody (ab121644)

ab121644 has not yet been referenced specifically in any publications.

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