Anti-muscarinic Acetylcholine Receptor 1 antibody (ab77098)

Overview

  • Product nameAnti-muscarinic Acetylcholine Receptor 1 antibody
    See all Muscarinic Acetylcholine Receptor 1 primary antibodies
  • Description
    Goat polyclonal to muscarinic Acetylcholine Receptor 1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog, Pig, Rhesus monkey, Orangutan
  • Immunogen

    Synthetic peptide:

    C-DKRRWRKIPKRPGSVH

    , corresponding to C terminal amino acids 438-453 of human muscarinic Acetylcholine Receptor 1 (NP_000729.2).

  • Positive control
    • Human brain lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab77098 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 51 kDa.

Target

  • RelevanceThe muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. Muscarinic receptors are so called as they are more sensitive to the effects of the alkaloid muscarine, rather than nicotine.
  • Cellular localizationCell Membrane; multi-pass membrane protein
  • Database links
  • Alternative names
    • AChR antibody
    • Cholinergic receptor muscarinic 1 antibody
    • CHRM1 antibody
    • HM1 antibody
    • M1 antibody
    • Muscarinic acetylcholine receptor M1 antibody
    see all

Anti-muscarinic Acetylcholine Receptor 1 antibody images

  • Anti-muscarinic Acetylcholine Receptor 1 antibody (ab77098) at 0.300000011921 µg/ml + human brain lysate (in RIPA buffer) at 35 µg

    Predicted band size : 51 kDa
    Observed band size : 48 kDa (why is the actual band size different from the predicted?)

References for Anti-muscarinic Acetylcholine Receptor 1 antibody (ab77098)

ab77098 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"