Anti-Muscarinic Acetylcholine Receptor M4 antibody - Cytoplasmic domain (ab150518)

Overview

  • Product name
    Anti-Muscarinic Acetylcholine Receptor M4 antibody - Cytoplasmic domain
    See all Muscarinic Acetylcholine Receptor M4 primary antibodies
  • Description
    Rabbit polyclonal to Muscarinic Acetylcholine Receptor M4 - Cytoplasmic domain
  • Host species
    Rabbit
  • Specificity
    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Guinea pig, Hamster, Cow, Dog, Pig, Gorilla
  • Immunogen

    Synthetic peptide, corresponding to 20 amino acids from the 3rd cytoplasmic domain of Human Muscarinic Acetylcholine Receptor M4 (NP_000732.2).

  • Positive control
    • Human brain, neurons and glia tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab150518 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance
    The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and postassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus.
  • Cellular localization
    Cell Membrane
  • Database links
  • Alternative names
    • AChR antibody
    • Cholinergic receptor muscarinic 4 antibody
    • Chrm 4 antibody
    • CHRM4 antibody
    • HM 4 antibody
    • HM4 antibody
    • M4 antibody
    • Muscarinic acetylcholine receptor M4 antibody
    see all

Images

  • Immunohistochemical analysis of Formalin-fixed, Paraffin-Embedded Human brain, neurons and glia tissue labeling Muscarinic Acetylcholine Receptor M4 with ab150518 at 3 µg/ml.

References

ab150518 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab150518.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up