The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution. Predicted molecular weight: 12 kDa.
Use at an assay dependent dilution.
FunctionMay control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC.
Tissue specificityHighly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung.
Sequence similaritiesBelongs to the AMY1 family.
Cellular localizationCytoplasm. Nucleus. Mitochondrion. Translocates into the nucleus in the S phase of the cell cycle upon an increase of MYC expression. Found in the mitochondria when associated with AKAP1.