The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 38 kDa. Dilution optimised using Chromogenic detection. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
RelevanceMycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65.
The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.
AraC family transcriptional regulator antibody
HTH-type transcriptional regulator VirS antibody
Putative virulence-regulating 38 kDa protein antibody
Virulence-regulating protein VirS antibody
Virulence-regulating transcriptional regulator VirS (AraC/XylS family) antibody
virulence-regulating transcriptional regulator VirS antibody
References for Anti-Mycobacterium tuberculosis 38kDa antibody [HTM82] (ab22743)
has not yet been referenced specifically in any publications.
Publishing research using ab22743? Please let us know so that we can cite the reference in this datasheet.
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