Anti-Mycobacterium tuberculosis (Hsp-65) antibody [3F7] (ab69618)

Overview

  • Product nameAnti-Mycobacterium tuberculosis (Hsp-65) antibody [3F7]
    See all Mycobacterium tuberculosis (Hsp-65) primary antibodies
  • Description
    Mouse monoclonal [3F7] to Mycobacterium tuberculosis (Hsp-65)
  • SpecificityCross reacts with hsp60 family members: Human, mouse, rat, cow, hamster, guinea pig, E. coli, and Drosophila
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with Mycobacterium bovis and Mycobacterium leprae.
  • Immunogen

    Recombinant protein isolated from Mycobacterium bovis

  • Positive control
    • GroEL Protein, Hsp60 Protein, Hsp65 Protein.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • PurityAmmonium Sulphate Precipitation
  • ClonalityMonoclonal
  • Clone number3F7
  • IsotypeIgM
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab69618 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 65 kDa.

Target

  • RelevanceMycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.
  • Cellular localizationCytoplasmic
  • Alternative names
    • 60 kDa chaperonin 2 antibody
    • 65 kDa antigen antibody
    • Antigen A antibody
    • Cell wall protein A antibody
    • groEL antibody
    • GroEL protein 2 antibody
    • GroEL2 antibody
    • Heat shock protein 65 antibody
    • Hsp65 antibody
    see all

References for Anti-Mycobacterium tuberculosis (Hsp-65) antibody [3F7] (ab69618)

ab69618 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab69618.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"