Anti-Myeloperoxidase antibody [2C7] (FITC) (ab11729)

Overview

• Product nameAnti-Myeloperoxidase antibody [2C7] (FITC)
  See all Myeloperoxidase primary antibodies
• Description
  Mouse monoclonal [2C7] to Myeloperoxidase (FITC)
• ConjugationFITC. Ex: 493nm, Em: 528nm
• Specificityab11729 recognises human myeloperoxidase.
• Tested applicationsSuitable for: IHC-Fr, Flow Cytmore details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Human myeloperoxidase

• General notesThis product should be stored undiluted. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Store at +4°C.
• Storage bufferPreservative: 0.09% Sodium Azide
  Constituents: 1% BSA, PBS, pH 7.4
• Concentration information loading...
• PurityProtein G purified
• Purification notesPurified IgG prepared by affinity chromatography.
• ClonalityMonoclonal
• Clone number2C7
• Myelomax63-Ag8.653
• IsotypeIgG1
• Research areas
  • Immunology
  • Innate Immunity
  • Macrophage / Inflamm.

  • Cardiovascular
  • Blood
  • Other

  • Cardiovascular
  • Vasculature
  • Vasculature Markers
  • Arterial

  • Cardiovascular
  • Vasculature
  • Vasculature Markers
  • Pulmonary

  • Cancer
  • Cancer Metabolism
  • Cellular metabolic process

  • Kits/ Lysates/ Other
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  • Kits/ Lysates/ Other
  • Kits
  • ELISA Kits
  • ELISA Kits
  • Cardiovascular ELISA kits

  • Metabolism
  • Pathways and Processes
  • Redox metabolism
  • Antioxidants

  • Metabolism
  • Types of disease
  • Cancer

Associated products

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

Applications

Target

• FunctionPart of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
• Involvement in diseaseDefects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
• Sequence similaritiesBelongs to the peroxidase family. XPO subfamily.
• Cellular localizationLysosome.

• Target information above from: UniProt accession P05164 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 4353 Human
  • Omim: 606989 Human
  • SwissProt: P05164 Human
  • Unigene: 458272 Human
• Alternative names
  • 84 kDa myeloperoxidase antibody
  • 89 kDa myeloperoxidase antibody
  • EC 1.11.1.7 antibody

  • EC1.11.2.2 antibody
  • fj80f04 antibody
  • MPO antibody
  • mpx antibody
  • myeloid-specific peroxidase antibody
  • Myeloperoxidase antibody
  • Myeloperoxidase heavy chain antibody
  • Myeloperoxidase light chain antibody
  • PERM_HUMAN antibody
  • wu:fj80f04 antibody

  see all