Anti-Myeloperoxidase antibody [2C7] (FITC) (ab11729)

Overview

• Product name
  Anti-Myeloperoxidase antibody [2C7] (FITC)
  See all Myeloperoxidase primary antibodies
• Description
  Mouse monoclonal [2C7] to Myeloperoxidase (FITC)
• Conjugation
  FITC. Ex: 493nm, Em: 528nm
• Specificity
  ab11729 recognises human myeloperoxidase.
• Tested applications
  Suitable for: IHC-Fr, Flow Cytmore details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Human myeloperoxidase

• General notes
  This product should be stored undiluted. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Store at +4°C.
• Storage buffer
  Preservative: 0.09% Sodium Azide
  Constituents: 1% BSA, PBS, pH 7.4
• Concentration information loading...
• Purity
  Protein G purified
• Purification notes
  Purified IgG prepared by affinity chromatography.
• Clonality
  Monoclonal
• Clone number
  2C7
• Myeloma
  x63-Ag8.653
• Isotype
  IgG1
• Research areas
  • Immunology
  • Innate Immunity
  • Macrophage / Inflamm.

  • Cardiovascular
  • Blood
  • Other

  • Cardiovascular
  • Vasculature
  • Vasculature Markers
  • Arterial

  • Cardiovascular
  • Vasculature
  • Vasculature Markers
  • Pulmonary

  • Cancer
  • Cancer Metabolism
  • Cellular metabolic process

  • Kits/ Lysates/ Other
  • Kits
  • ELISA Kits
  • ELISA Kits
  • Cancer proteins ELISA kits

  • Kits/ Lysates/ Other
  • Kits
  • ELISA Kits
  • ELISA Kits
  • Cardiovascular ELISA kits

  • Metabolism
  • Pathways and Processes
  • Redox metabolism
  • Antioxidants

  • Metabolism
  • Types of disease
  • Cancer

Associated products

• Assay kits
  • Myeloperoxidase (MPO) Activity Assay Kit (Colorimetric) (ab105136)
  • Myeloperoxidase (MPO) Activity Assay Kit (Fluorometric) (ab111749)
• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

Applications

Target

• Function
  Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
• Involvement in disease
  Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
• Sequence similarities
  Belongs to the peroxidase family. XPO subfamily.
• Cellular localization
  Lysosome.

• Target information above from: UniProt accession P05164 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 4353 Human
  • Omim: 606989 Human
  • SwissProt: P05164 Human
  • Unigene: 458272 Human
• Alternative names
  • 84 kDa myeloperoxidase antibody
  • 89 kDa myeloperoxidase antibody
  • EC 1.11.1.7 antibody

  • EC1.11.2.2 antibody
  • fj80f04 antibody
  • MPO antibody
  • mpx antibody
  • myeloid-specific peroxidase antibody
  • Myeloperoxidase antibody
  • Myeloperoxidase heavy chain antibody
  • Myeloperoxidase light chain antibody
  • PERM_HUMAN antibody
  • wu:fj80f04 antibody

  see all

Protocols

• Flow cytometry protocols
• Immunohistochemistry protocols