Anti-Myeloperoxidase antibody [59A5] (ab88846)

Overview

  • Product nameAnti-Myeloperoxidase antibody [59A5]
    See all Myeloperoxidase primary antibodies
  • Description
    Mouse monoclonal [59A5] to Myeloperoxidase
  • SpecificityThis antibody stains strongly with the cytoplasm of myeloid cells. The antibody detects myeloperoxidase found in myeloid cells of acute myeloid leukemia.
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant protein from exon 7 of the Human Myeloperoxidase.

  • Positive control
    • Tonsil

Properties

Applications

Our Abpromise guarantee covers the use of ab88846 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: Ready to use. Sections require high temperature antigen unmasking with 10mM citrate buffer, pH 6.0 prior to immunostaining.

    Is unsuitable for IHC-Fr.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionPart of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
    • Involvement in diseaseDefects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
    • Sequence similaritiesBelongs to the peroxidase family. XPO subfamily.
    • Cellular localizationLysosome.
    • Information by UniProt
    • Database links
    • Alternative names
      • 84 kDa myeloperoxidase antibody
      • 89 kDa myeloperoxidase antibody
      • EC 1.11.1.7 antibody
      • EC1.11.2.2 antibody
      • fj80f04 antibody
      • MPO antibody
      • mpx antibody
      • myeloid-specific peroxidase antibody
      • Myeloperoxidase antibody
      • Myeloperoxidase heavy chain antibody
      • Myeloperoxidase light chain antibody
      • PERM_HUMAN antibody
      • wu:fj80f04 antibody
      see all

    References for Anti-Myeloperoxidase antibody [59A5] (ab88846)

    ab88846 has not yet been referenced specifically in any publications.

    Product Wall



    I can confirm that a light green staining of the antibody solution in the vial is normal. ab88846 is provided as tissue culture supernatant. Therefore is contains medium including the blueish dye that indicates the pH of the medium (usually p...

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