Anti-Myeloperoxidase antibody [7,17] (FITC) (ab91237)

Overview

  • Product nameAnti-Myeloperoxidase antibody [7,17] (FITC)
    See all Myeloperoxidase primary antibodies
  • Description
    Mouse monoclonal [7,17] to Myeloperoxidase (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • Specificityab91237 reacts with virtually all cells of the myeloid lineage (from myekloblast to neutrophils and monocytes). ab91237 does not react with Human lymphocytes, thrombocytes and erythrocytes. 96% of all AML's are found positive; 100% of all ALL's are found negative.
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human myeloperoxidase from CML cells

  • Positive control
    • Normal Human peripheral blood

Properties

Applications

Our Abpromise guarantee covers the use of ab91237 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notesFlow Cyt: Use 20 µl for 106 cells.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionPart of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
    • Involvement in diseaseDefects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
    • Sequence similaritiesBelongs to the peroxidase family. XPO subfamily.
    • Cellular localizationLysosome.
    • Information by UniProt
    • Database links
    • Alternative names
      • 84 kDa myeloperoxidase antibody
      • 89 kDa myeloperoxidase antibody
      • EC 1.11.1.7 antibody
      • EC1.11.2.2 antibody
      • fj80f04 antibody
      • MPO antibody
      • mpx antibody
      • myeloid-specific peroxidase antibody
      • Myeloperoxidase antibody
      • Myeloperoxidase heavy chain antibody
      • Myeloperoxidase light chain antibody
      • PERM_HUMAN antibody
      • wu:fj80f04 antibody
      see all

    Anti-Myeloperoxidase antibody [7,17] (FITC) images

    • ab91237, at 20 µl / 106 cells, staining Myeloperoxidase in normal Human peripheral blood, by Flow Cytometry.

    References for Anti-Myeloperoxidase antibody [7,17] (FITC) (ab91237)

    ab91237 has not yet been referenced specifically in any publications.

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