Overview

  • Product name
  • Description
    Rabbit polyclonal to MYO1A
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    A recombinant fragment corresponding to a region within amino acids 299-547 of Human MYO1A (Uniprot ID Q9UBC5).

  • Positive control
    • Jurkat, Raji, K562 and NCI-H929 whole cell lysates. Human colon carcinoma tissue.
  • General notes
    Store as a concentrated solution.

Properties

Applications

Our Abpromise guarantee covers the use of ab154518 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 118 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function
    Involved in directing the movement of organelles along actin filaments.
  • Involvement in disease
    Defects in MYO1A are the cause of deafness autosomal dominant type 48 (DFNA48) [MIM:607841]. DFNA48 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
  • Sequence similarities
    Contains 3 IQ domains.
    Contains 1 myosin head-like domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • BBM I antibody
    • BBM-I antibody
    • BBMI antibody
    • Brush border myosin I antibody
    • DFNA48 antibody
    • MIHC antibody
    • MYHL antibody
    • Myo1a antibody
    • MYO1A_HUMAN antibody
    • Myosin I heavy chain antibody
    • Myosin, heavy polypeptide like (100kD) antibody
    • Myosin-IA antibody
    see all

Images

  • All lanes : Anti-MYO1A antibody (ab154518) at 1/2000 dilution

    Lane 1 : Jurkat whole cell lysate
    Lane 2 : Raji whole cell lysate
    Lane 3 : K562 whole cell lysate
    Lane 4 : NCI H929 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 118 kDa
  • Immunohistochemical analysis of paraffin-embedded Human colon carcinoma, labeling MYO1A using ab154518 at 1/500 dilution.

References

ab154518 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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