Overview

  • Product nameAnti-MYO1E antibody
    See all MYO1E primary antibodies
  • Description
    Rabbit polyclonal to MYO1E
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within the internal sequence amino acids 1043-1092 of Human MYO1E (NP_004989).

  • Positive control
    • HepG2 cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab98191 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 127 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionMyosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14.
  • Tissue specificityExpressed in the immune system. In the kidney, predominantly expressed in the glomerulus, including podocytes.
  • Involvement in diseaseFocal segmental glomerulosclerosis 6
  • Sequence similaritiesBelongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    Contains 1 IQ domain.
    Contains 1 myosin motor domain.
    Contains 1 SH3 domain.
    Contains 1 TH1 (class I myosin tail homology) domain.
  • Cellular localizationCytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Cytoplasmic vesicle, clathrin-coated vesicle. Cell junction. Colocalizes with F-actin (By similarity). In cultured podocytes, it localizes close to and is associated with the cytoplasmic membrane, with enrichment at the lamellipodia tips. Colocalizes with cytoplasmic vesicles, including endocytic clathrin-coated vesicles. Colocalizes with dynamin at cytoplasmic vesicles.
  • Information by UniProt
  • Database links
  • Alternative names
    • FSGS6 antibody
    • HuncM-IC antibody
    • MYO1C antibody
    • Myo1e antibody
    • MYO1E variant protein antibody
    • MYO1E_HUMAN antibody
    • Myosin heavy chain myr 3 antibody
    • Myosin IC, formerly antibody
    • Myosin IE antibody
    • Myosin-Ic antibody
    • Myr 3 antibody
    • Myr3 antibody
    • MYR5 antibody
    • Unconventional myosin 1E antibody
    • Unconventional myosin Ie antibody
    • Unconventional myosin-Ie antibody
    see all

Anti-MYO1E antibody images

  • Anti-MYO1E antibody (ab98191) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 127 kDa

References for Anti-MYO1E antibody (ab98191)

ab98191 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab98191.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"