The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution.
Use a concentration of 1 - 5 µg/ml. Detects a band of approximately 186 kDa (predicted molecular weight: 186 kDa).
FunctionProbable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing.
Tissue specificityStrongest expression in retina, retinal pigment epithelial cells, cochlea and pancreas.
Involvement in diseaseDeafness, autosomal recessive, 30
Sequence similaritiesIn the N-terminal section; belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. Contains 3 IQ domains. Contains 1 myosin head-like domain. Contains 1 protein kinase domain.