Overview

  • Product name
  • Description
    Goat polyclonal to MYO5A
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chicken, Pig
  • Immunogen

    Synthetic peptide:

    C-ETKQLELDLN

    , corresponding to internal sequence amino acids 1063-1072 of Human MYO5A (NP_000250.3; NP_001135967.1).

  • Positive control
    • Jurkat cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab105024 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 200 kDa (predicted molecular weight: 215 kDa).Can be blocked with MYO5A peptide (ab201110).

Target

  • Function
    Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.
  • Tissue specificity
    Detected in melanocytes.
  • Involvement in disease
    Griscelli syndrome 1
    Griscelli syndrome 3
    Elejalde syndrome
  • Sequence similarities
    Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    Contains 1 dilute domain.
    Contains 6 IQ domains.
    Contains 1 myosin motor domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • non-muscle antibody
    • Dilute myosin heavy chain antibody
    • GS1 antibody
    • MYH12 antibody
    • MYO5 antibody
    • Myo5a antibody
    • MYO5A_HUMAN antibody
    • Myosin heavy chain 12 antibody
    • Myosin heavy polypeptide kinase antibody
    • Myosin V antibody
    • Myosin VA (heavy polypeptide 12 myoxin) antibody
    • Myosin VA (heavy polypeptide 12 myoxin) antibody
    • Myosin-12 antibody
    • Myoxin antibody
    • MYR12 antibody
    • Unconventional myosin-Va antibody
    see all

Images

  • Anti-MYO5A antibody (ab105024) at 1 µg/ml + Jurkat cell lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 215 kDa

References

ab105024 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab105024.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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