Overview

  • Product name
  • Description
    Rabbit polyclonal to MyoGEF
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human MyoGEF aa 60-87 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).
    Database link: 55200

  • Positive control
    • NCI-H460 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab91412 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 89 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      MyoGEF functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis
    • Cellular localization
      Cytoplasm; cytoskeleton, spindle pole.
    • Database links
    • Alternative names
      • FLJ10665 antibody
      • MGC126315 antibody
      • MGC126353 antibody
      • MGC126354 antibody
      • Myosin interacting guanine nucleotide exchange factor antibody
      • PH domain containing family G member 6 antibody
      • Pleckstrin homology domain containing family G (with RhoGef domain) member 6 antibody
      • Pleckstrin homology domain-containing family G member 6 antibody
      • PLEKHG6 antibody
      see all

    Images

    • Anti-MyoGEF antibody (ab91412) at 1/100 dilution + NCI-H460 cell lysate at 35 µg

      Predicted band size : 89 kDa

    References

    ab91412 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab91412.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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