Recombinant
RabMAb

Anti-Myosin VIIa antibody [EPR7498] (ab155984)

Overview

  • Product name
    Anti-Myosin VIIa antibody [EPR7498]
    See all Myosin VIIa primary antibodies
  • Description
    Rabbit monoclonal [EPR7498] to Myosin VIIa
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
    Unsuitable for: Flow Cyt,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human Myosin VIIa (UniProt Q13402).

  • Positive control
    • Y79 cell lysates; A97 cells.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab155984 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 254 kDa.
ICC/IF 1/100 - 1/250.
  • Application notes
    Is unsuitable for Flow Cyt,IHC-P or IP.
  • Target

    • Relevance
      Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. In retina, myosin VIIa may play a role in trafficking of ribbon-synaptic vesicle complexes and renewal of the outer photoreceptors disks. In inner ear, it may maintain the rigidity of stereocilia during the dynamic movements of the bundle.
    • Cellular localization
      Cytoplasmic, cytoskeleton
    • Database links
    • Alternative names
      • Deafness autosomal dominant 11 antibody
      • Deafness autosomal recessive 2 antibody
      • DFNA11 antibody
      • DFNB 2 antibody
      • DFNB2 antibody
      • Myo7a antibody
      • Myosin 7a antibody
      • Myosin VIIA (Usher syndrome 1B (autosomal recessive, severe)) antibody
      • Myosin VIIa antibody
      • Myosin, unconventional, family VII, member A antibody
      • MYOVIIA antibody
      • MYU7A antibody
      • NSRD 2 antibody
      • NSRD2 antibody
      • Unconventional myosin VIIa antibody
      • Ush 1B antibody
      • Ush1b antibody
      • Usher syndrome 1B antibody
      see all

    Images

    • Anti-Myosin VIIa antibody [EPR7498] (ab155984) at 1/1000 dilution + Y79 cell lysate at 10 µg

      Secondary
      Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size: 254 kDa

    • Immunofluorescence analysis of Y79 cells, staining Myosin VIIa with ab155984 at 1/100 dilution.

    References

    ab155984 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab155984.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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