Overview

  • Product name
  • Description
    Goat polyclonal to MYRIP
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Pig
  • Immunogen

    Synthetic peptide:

    C-KDLMEPALESAVMY

    , corresponding to C terminal amino acids 846-859 of Human MYRIP.

  • Positive control
    • Human brain (cortex), breast and colon (submucosal plexus) tissues; Human duodenum lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab113665 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 96 kDa.
ELISA 1/64000.
IHC-P Use a concentration of 3.75 µg/ml.

Target

  • Function
    Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments.
  • Tissue specificity
    Detected in brain, skin, heart, adrenal medulla, pancreas, intestine, liver, kidney, muscle and testis.
  • Sequence similarities
    Contains 1 FYVE-type zinc finger.
    Contains 1 RabBD (Rab-binding) domain.
  • Cellular localization
    Cytoplasm. In pre- and post-synaptic areas in photoreceptor cells and in the basal microvilli of retinal pigment epithelium cells. Associated with melanosomes. Colocalizes with actin filaments.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp586F1018 antibody
    • Exophilin 8 antibody
    • Exophilin antibody
    • Exophilin-8 antibody
    • Exophilin8 antibody
    • FLJ44025 antibody
    • MGC130034 antibody
    • MGC130035 antibody
    • Myosin VIIA and Rab interacting protein antibody
    • Myosin-VIIa- and Rab-interacting protein antibody
    • Myrip antibody
    • MYRIP_HUMAN antibody
    • Rab effector MyRIP antibody
    • SLAC 2C antibody
    • SLAC2 C antibody
    • SlaC2-c antibody
    • SLAC2C antibody
    • Slp homolog lacking C2 domains c antibody
    • Slp homologue lacking C2 domains antibody
    • Slp homologue lacking C2 domains c antibody
    • Synaptotagmin like protein homologue lacking C2 domains c antibody
    • synaptotagmin-like protein lacking C2 domains C antibody
    see all

Images

  • Anti-MYRIP antibody (ab113665) at 0.1 µg/ml + Human duodenum lysate (in RIPA buffer) at 35 µg

    Predicted band size : 96 kDa
  • ab113665, at 3.75 µg/ml, staining MYRIP in formalin fixed, paraffin embedded Human brain (cortex) tissue by Immunohistochemistry.
  • ab113665, at 3.75 µg/ml, staining MYRIP in formalin fixed, paraffin embedded Human breast tissue by Immunohistochemistry.
  • ab113665, at 3.75 µg/ml, staining MYRIP in formalin fixed, paraffin embedded Human colon (submucosal plexus) tissue by Immunohistochemistry.

References

ab113665 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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