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n-Myc peptide (ab31595)

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Overview

Product name

n-Myc peptide
See all n-Myc products (3) ...

Protein description

Synthetic peptide derived from within residues 1 - 100 of Human n-Myc. (Note: the amino acid sequence is proprietary) This peptide was used as an immunogen for ab24193 .

Protein length

464 amino acids

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Information available upon request.

Concentration

Concentration information loading...

Research areas

Cancer >> Oncoproteins/suppressors >> Oncoproteins >> Transcription factors
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH / Leucine Zipper
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper

Applications

Application notes

This peptide can be used with studies using ab24193.

Protein info

Function

May function as a transcription factor.

Involvement in disease

Note=Amplification of the N-MYC gene is associated with a variety of human tumors, most frequently neuroblastoma, where the level of amplification appears to increase as the tumor progresses.
Defects in MYCN are the cause of microcephaly-oculo-digito-esophageal-duodenal syndrome (MODED) [MIM:164280]; also known as oculodigitoesophagoduodenal syndrome (ODED). Microcephaly-oculo-digito-esophageal-duodenal syndrome is characterized by variable combinations of esophageal and duodenal atresias, microcephaly, learning disability and limb malformations. Cardiac and renal malformations, vertebral anomalies, and deafness have also been described.
Defects in MYCN are the cause of microcephaly and digital abnormalities with normal intelligence (MCPHDANI) [MIM:602585].

Sequence similarities

Contains 1 basic helix-loop-helix (bHLH) domain.

Developmental stage

Expressed during fetal development.

Cellular localization

Nucleus.

Target information above from: UniProt accessionP04198 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

References for n-Myc peptide (ab31595)

ab31595 has not yet been referenced specifically in any publications.

Publishing research using ab31595? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"