Mouse monoclonal [81D4] to N epsilon gamma glutamyl Lysine
SpecificityReacts with Ne (g-L-glutamyl)-L-lysine.
Cross reacts in ELISA with N1,N4 bis (gPoly L-glutamyl) Putrescine and N1,N8 bis (gPoly L-glutamyl) Spermidine.
There is no cross reaction with:
- protein bound Ne acetyl lysine
- protein bound N1 or N4 mono (gPoly L-glutamyl) Putrescine
- protein bound N1 mono (gPoly L-glutamyl) Spermidine
- protein bound Ne (g -L-glutamyl) lysine having a free alpha amine either on its glutamyl or lysyl moieties
ab424 staining N epsilon gamma glutamyl Lysine in kidney tissue sections by Immunohistochemistry (Frozen sections). Sections A through D were stained for insoluble tissue transglutaminase, while E through H were stained for N epsilon gamma glutamyl Lysine crosslink. A, B, E, F were control kidneys; C, D, G, H were diseased kidneys showing increased staining in the expanded interstitium, the mesangium and periglomerular.
References for Anti-N epsilon gamma glutamyl Lysine antibody [81D4] (ab424)
Assi J et al. Transglutaminase 2 overexpression in tumor stroma identifies invasive ductal carcinomas of breast at high risk of recurrence. PLoS One8:e74437 (2013).
Read more (PubMed: 24058567) »