Biological descriptionPotent, selective D3 antagonist (Ki values are 0.52 nM (D3), 269 nM (D4) and 5 nM (D2)).
Storage instructionsStore at Room Temperature. Store under Desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in 1eq. HCl to 50 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Audinot V et al. A comparative in vitro and in vivo pharmacological characterization of the novel dopamine D3 receptor antagonists (+)-S 14297, nafadotride, GR 103,691 and U 99194. J Pharmacol Exp Ther287:187-97 (1998).
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