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Rabbit polyclonal to NAGS
HumanPredicted to work with:
Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish
A region within synthetic peptide: PVLGGTPYLD KFVVSSSRQG QGSGQMLWEC LRRDLQTLFW RSRVTNPINP, corresponding to C terminal amino acids 434-483 of Human NAGS
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 2% Sucrose, PBS
Concentration information loading...
Protein A purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1.25 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 58 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Plays a role in the regulation of ureagenesis by producing variable amounts of N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPSI) activity.
Highly expressed in the adult liver, kidney and small intestine. Weakly expressed in the fetal liver, lung, pancreas, placenta, heart and brain tissue.
Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.
Involvement in disease
N-acetylglutamate synthase deficiency
Belongs to the acetyltransferase family.
Contains 1 N-acetyltransferase domain.
Probably processed by mitochondrial processing peptidase (MPP). The long form has not yet been isolated.
Information by UniProt
- 1700120E20Rik antibody
- AGAS antibody
- AI415708 antibody
Western blot - Anti-NAGS antibody (ab65536)
has not yet been referenced specifically in any publications.
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