Anti-NALP5 antibody (ab105324)
Key features and details
- Rabbit polyclonal to NALP5
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NALP5 antibody
See all NALP5 primary antibodies -
Description
Rabbit polyclonal to NALP5 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, ICC/IFmore details -
Species reactivity
Reacts with: Human -
Immunogen
A Synthetic peptide (14 amino acid) from near the C terminus of Human NALP5 (NP_703148).
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab105324 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use at an assay dependent concentration.
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ICC/IF |
Use a concentration of 20 µg/ml.
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Notes |
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IHC-P
Use at an assay dependent concentration. |
ICC/IF
Use a concentration of 20 µg/ml. |
Target
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Function
As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions. -
Tissue specificity
Oocyte-specific. -
Sequence similarities
Belongs to the NLRP family.
Contains 13 LRR (leucine-rich) repeats.
Contains 1 NACHT domain.
Contains 1 pyrin domain. -
Cellular localization
Mitochondrion. Nucleus, nucleolus. Cytoplasm. In the subcortical cytoplasm of early embryos from the 1-cell to the blastocyst stages. From the 2-cell stage, still detected in the subcortex, but excluded from cell-cell contact regions (By similarity). - Information by UniProt
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Database links
- Entrez Gene: 126206 Human
- Omim: 609658 Human
- SwissProt: P59047 Human
- Unigene: 356872 Human
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Alternative names
- CLR19.8 antibody
- MATER antibody
- Mater protein homolog antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab105324 has not yet been referenced specifically in any publications.