Overview

  • Product name
  • Description
    Rabbit polyclonal to NALP5
  • Tested applications
    Suitable for: IHC-P, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A Synthetic peptide (14 amino acid) from near the C terminus of Human NALP5 (NP_703148).

  • Positive control
    • Mouse Brain Tissue Lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab105324 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 134 kDa.

Target

  • Function
    As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions.
  • Tissue specificity
    Oocyte-specific.
  • Sequence similarities
    Belongs to the NLRP family.
    Contains 13 LRR (leucine-rich) repeats.
    Contains 1 NACHT domain.
    Contains 1 pyrin domain.
  • Cellular localization
    Mitochondrion. Nucleus, nucleolus. Cytoplasm. In the subcortical cytoplasm of early embryos from the 1-cell to the blastocyst stages. From the 2-cell stage, still detected in the subcortex, but excluded from cell-cell contact regions (By similarity).
  • Information by UniProt
  • Database links
  • Alternative names
    • CLR19.8 antibody
    • MATER antibody
    • Mater protein homolog antibody
    • Maternal antigen that embryos require antibody
    • NACHT, leucine rich repeat and PYD containing 5 antibody
    • NACHT, LRR and PYD domains-containing protein 5 antibody
    • NALP5_HUMAN antibody
    • NLR family, pyrin domain containing 5 antibody
    • NLRP5 antibody
    • Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5 antibody
    • PAN11 antibody
    • PYPAF8 antibody
    see all

Images

  • Immunofluorescence of NALP5 in Human brain tissue with ab105324 at 20 ug/mL.

  • Immunohistochemistry of Human brain tissue with ab105324 at 10 μg/mL.

References

ab105324 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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