Overview

  • Product name
  • Description
    Goat polyclonal to NAT10
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog
  • Immunogen

    Synthetic peptide: C-

    KSDKKRKLEAKQ

    , corresponding to internal sequence (near the C terminal) amino acids 989 - 1000 of Human NAT10 (NP_078938.1)

Properties

Applications

Our Abpromise guarantee covers the use of ab78600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3 - 6 µg/ml.

Target

  • Function
    Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.
  • Sequence similarities
    Belongs to the UPF0202 family.
    Contains 1 N-acetyltransferase domain.
  • Cellular localization
    Nucleus > nucleolus. Nucleolar in interphase and redistributes to the perichromosomal layer and to the midbody during telophase.
  • Information by UniProt
  • Database links
  • Alternative names
    • ALP antibody
    • DKFZp434C116 antibody
    • FLJ10774 antibody
    • FLJ12179 antibody
    • FLJ23850 antibody
    • hALP antibody
    • KIAA1709 antibody
    • N acetyltransferase 10 antibody
    • N acetyltransferase 10 GCN5 related antibody
    • N acetyltransferase like antibody
    • N acetyltransferase like protein antibody
    • N-acetyltransferase 10 antibody
    • NAT10 antibody
    • NAT10_HUMAN antibody
    • NET43 antibody
    see all

Images

  • ab78600 at 3.8 µg/ml staining NAT10 in Human colon by Immunohistochemsitry (Formalin/PFA-fixed paraffin-embedded sections). Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

References

ab78600 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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