The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
FunctionMay have a lysine N-acetyltransferase activity catalyzing peptidyl-lysine N6-acetylation of various proteins. Thereby, may regulate apoptosis through the acetylation and the regulation of the expression of PROM1 (PubMed:24556617). May also regulate amyloid beta-peptide secretion through acetylation of BACE1 and the regulation of its expression in neurons (PubMed:19011241).
Sequence similaritiesBelongs to the camello family. Contains 1 N-acetyltransferase domain.
Cellular localizationEndoplasmic reticulum-Golgi intermediate compartment membrane. Endoplasmic reticulum membrane. Enriched in the Endoplasmic reticulum-Golgi intermediate compartment.