Anti-Natriuretic Peptide Receptor C antibody [OTI11H6] (ab123957)

Overview

  • Product nameAnti-Natriuretic Peptide Receptor C antibody [OTI11H6]
    See all Natriuretic Peptide Receptor C primary antibodies
  • Description
    Mouse monoclonal [OTI11H6] to Natriuretic Peptide Receptor C
  • Tested applicationsSuitable for: WB, IHC-P, Flow Cyt, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length Human Natriuretic Peptide Receptor C protein produced in HEK293T cells (NP_000899).

  • Positive control
    • HEK293T cells transfected with pCMV6-ENTRY Natriuretic Peptide Receptor C cDNA; Human kidney, liver and liver carcinoma tissues; COS7 cells transiently transfected by pCMV6-ENTRY Natriuretic Peptide Receptor C; HeLa and HT29 cells; HEK293T cells transfected with pCMV6-ENTRY Natriuretic Peptide Receptor C.
  • General notesDilute in PBS (pH7.3) before use.

Properties

Applications

Our Abpromise guarantee covers the use of ab123957 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 60 kDa.
IHC-P 1/50.
Flow Cyt 1/100. ab170192-Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
ICC/IF 1/100.

Target

  • FunctionReceptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
  • Sequence similaritiesBelongs to the ANF receptor family.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ANP C antibody
    • ANP-C antibody
    • ANPC antibody
    • ANPR-C antibody
    • ANPRC antibody
    • ANPRC_HUMAN antibody
    • Atrial natriuretic peptide C type receptor antibody
    • Atrial natriuretic peptide clearance receptor antibody
    • Atrial natriuretic peptide receptor 3 antibody
    • Atrial natriuretic peptide receptor type C antibody
    • Atrionatriuretic peptide receptor C antibody
    • C5orf23 antibody
    • FLJ14054 antibody
    • GUCY2B antibody
    • MGC22189 antibody
    • Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) antibody
    • Natriuretic peptide receptor C/guanylate cyclase C antibody
    • NPR 3 antibody
    • NPR C antibody
    • NPR-C antibody
    • Npr3 antibody
    • NPRC antibody
    see all

Anti-Natriuretic Peptide Receptor C antibody [OTI11H6] images

  • All lanes : Anti-Natriuretic Peptide Receptor C antibody [OTI11H6] (ab123957) at 1/2000 dilution

    Lane 1 : HEK293T cells transfected with pCMV6-ENTRY control cDNA
    Lane 2 : HEK293T cells transfected with pCMV6-ENTRY Natriuretic Peptide Receptor C cDNA

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 60 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC219453)
  • ab123957, at 1/50 dilution, staining Natriuretic Peptide Receptor C in paraffin-embedded Human kidney tissue by Immunohistochemistry.
  • ab123957, at 1/50 dilution, staining Natriuretic Peptide Receptor C in paraffin-embedded Human liver tissue by Immunohistochemistry.
  • ab123957, at 1/50 dilution, staining Natriuretic Peptide Receptor C in paraffin-embedded Human liver carcinoma tissue by Immunohistochemistry.
  • ab123957, at 1/100 dilution, staining Natriuretic Peptide Receptor C in COS7 cells transiently transfected by pCMV6-ENTRY Natriuretic Peptide Receptor C by Immunofluorescence.
  • ab123957, at 1/100 dilution, staining Natriuretic Peptide Receptor C in HeLa cells by Immunofluorescence.
  • ab123957, at 1/100 dilution, staining Natriuretic Peptide Receptor C in HT29 cells by Immunofluorescence.
  • ab123957 at 1/100 dilution staining Natriuretic Peptide Receptor C in HEK293T cells transfected with either pCMV6-ENTRY Natriuretic Peptide Receptor C (Red) or empty vector control plasmid (Blue) by Flow Cytometry.

References for Anti-Natriuretic Peptide Receptor C antibody [OTI11H6] (ab123957)

ab123957 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"