Anti-Natriuretic peptides A antibody (ab126149)

Overview

  • Product name
    Anti-Natriuretic peptides A antibody
    See all Natriuretic peptides A primary antibodies
  • Description
    Rabbit polyclonal to Natriuretic peptides A
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Recombinant full length protein corresponding to Human Natriuretic peptides A.
    Database link: P01160

  • Positive control
    • NT2D1 whole cell lysate, PC-3 whole cell lysate, Mouse heart whole cell lysate, Human Hepatoma tissue and Human muscle tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab126149 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 16 kDa.
IHC-P 1/100 - 1/500. Perform antigen retrieval using heat mediated 10mM Citrate buffer(pH6.0) or Tris-EDTA buffer (pH8.0)

Target

  • Function
    Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • Involvement in disease
    Atrial standstill 2
    Atrial fibrillation, familial, 6
  • Sequence similarities
    Belongs to the natriuretic peptide family.
  • Post-translational
    modifications
    Cleaved by CORIN upon secretion to produce the functional hormone.
    Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • ANF antibody
    • ANF_HUMAN antibody
    • ANP antibody
    • ATFB6 antibody
    • Atrial natriuretic factor antibody
    • Atrial natriuretic peptide antibody
    • Atriopeptin antibody
    • Cardiodilatin antibody
    • Cardiodilatin related peptide antibody
    • Cardiodilatin-related peptide antibody
    • Cardionatrin antibody
    • CDD ANF antibody
    • CDD antibody
    • CDD-ANF antibody
    • CDP antibody
    • Natriuretic peptide A antibody
    • Natriuretic peptide precursor A antibody
    • NPPA antibody
    • PND antibody
    • Prepronatriodilatin antibody
    see all

Images

  • All lanes : Anti-Natriuretic peptides A antibody (ab126149) at 1/1000 dilution

    Lane 1 : NT2D1 whole cell lysate
    Lane 2 : PC-3 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 16 kDa
    15% SDS PAGE
  • Anti-Natriuretic peptides A antibody (ab126149) at 1/5000 dilution + Mouse heart whole cell lysate at 50 µg

    Predicted band size : 16 kDa
    15% SDS PAGE
  • ab126149, at 1/500 dilution, staining Natriuretic peptides A in Formalin-fixed, Paraffin-embedded Human hepatoma tissue by Immunohistochemistry.

  • ab126149, at 1/500 dilution, staining Natriuretic peptides A in Formalin-fixed, Paraffin-embedded Human muscle tissue by Immunohistochemistry.

References

ab126149 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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