Natural Clostridium difficile Toxin A protein (ab123999)

Overview

  • Product nameNatural Clostridium difficile Toxin A protein
  • Protein lengthFull length protein

Description

  • NatureNatural
  • SourceNative
  • Amino Acid Sequence
    • AccessionP16154
    • Molecular weight308 kDa
    • Amino acids1 to 2710

Specifications

Our Abpromise guarantee covers the use of ab123999 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    Clostridium difficile Toxin A has been highly purified
  • FormLyophilised
  • Additional notesThis protein is derived from a pathogenic organism, and may be involved in a disease process, consequently exposure may have adverse health effects.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C. Avoid freeze / thaw cycle.

    Constituents: 1.19% HEPES, 5% Sucrose, 0.88% Sodium chloride

  • ReconstitutionReconstitute in 250µl sterile distilled water.

General Info

  • Alternative names
    • tcdA
    • toxA
  • RelevanceClostridium difficile, or C. difficile, a gram positive anaerobic bacterium, is the major causative agent of colitis and diarrhea that can occur following antibiotic intake. C. difficile infection is one of the most common hospital acquired infections. When C. difficile colonize the gut, they release two potent toxins, toxin A and toxin B, which bind to certain receptors in the lining of the colon and ultimately cause diarrhoea and inflammation of the large intestine.
  • Cellular localizationSecreted

Natural Clostridium difficile Toxin A protein images

  • SDS-PAGE showing ab123999 at 308 kDa

References for Natural Clostridium difficile Toxin A protein (ab123999)

ab123999 has not yet been referenced specifically in any publications.

Product Wall



These products were purified from Clostridium difficile strain VPI10463 (which produces toxinotype 0 toxins). The toxins are active, each batch is tested by verocytotoxicity assay and demonstrated to be toxic to cells down to at least 5 ng/ml...

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Thank you for contacting us.

In response to your questions:

1)The toxin is guaranteed to be stable for at least 1 month after reconstitution, (we have data that shows 6 weeks is still fine).

2)The toxin can be frozen for l...

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Vielen Dank für Ihren Anruf.

Zu den Toxinen kann ich Ihnen folgende Informationen aus dem Labor weiterleiten:

Clostridium difficile Toxin A Protein ab123999und Clostridium difficile Toxin B Protein ab124001werden aus demClostri...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"