Natural Clostridium difficile Toxoid B protein (ab124002)

Overview

  • Product nameNatural Clostridium difficile Toxoid B protein
  • Protein lengthFull length protein

Description

  • NatureNatural
  • SourceNative
  • Amino Acid Sequence
    • Molecular weight270 kDa

Specifications

Our Abpromise guarantee covers the use of ab124002 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    ELISA

  • Purity> 95 % SDS-PAGE.

  • FormLyophilised
  • Additional notesInactivation: Inactivated using formaldehyde. No cell rounding in the sensitive verocytotoxicity assay at 2µg/ml compared to active toxin lethal dose of 4pg/ml.
    Antigenicity: Maintained to be no less than 90% of original toxin strength as measured by direct ELISA.

    This protein is derived from a pathogenic organism, and may be involved in a disease process, consequently exposure may have adverse health effects.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    Constituents: 1.19% HEPES, 5% Sucrose, 0.88% Sodium chloride

  • ReconstitutionReconstitute in 250µl sterile distilled water.

General Info

  • RelevanceClostridium difficile, or C. difficile, a gram positive anaerobic bacterium, is the major causative agent of colitis and diarrhoea that can occur following antibiotic intake. C. difficile infection is one of the most common hospital acquired infections. When C. difficile colonize the gut, they release two potent toxins, toxin A and toxin B, which bind to certain receptors in the lining of the colon and ultimately cause diarrhoea and inflammation of the large intestine.

Natural Clostridium difficile Toxoid B protein images

  • SDS-PAGE showing ab124002 at 270kDa.

References for Natural Clostridium difficile Toxoid B protein (ab124002)

ab124002 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"