Overview

Description

  • NatureNatural
  • SourceNative
  • Amino Acid Sequence
    • SpeciesCow
    • Amino acids0 to 0

Specifications

Our Abpromise guarantee covers the use of ab89813 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

  • Purity> 95 % SDS-PAGE.
    Purity was determined to be >95% by densitometry.
  • FormLiquid
  • Additional notes

    ab89813 (Histone H1 protein) can be utilized as a substrate for the following active protein Kinases:

     

    ab104618 (Active human CDK1 + CCNB1 full length protein)
    ab64299 (Active human CDK1 + Cyclin A2 full length protein)
    ab51407 (Active human CDK2 + Cyclin A2 full length protein)
    ab85639 (Active human CDK2 + CCNE1 full length protein)
    ab177582 (Active human CCNO full length protein)
    ab85643 (Active human CDK3 + CCNE1 full length protein)
    ab60761 (Human p35 + p25 full length protein)

    ab177586 (Active human PCTAIRE1 protein fragment)
    ab177576 (Active human PFTK1 (CDK14)/CyclinY full length protein)

     

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50mM Tris HCl, 150mM Sodium chloride, pH 7.5

General Info

  • Alternative names
    • dJ221C16.2
    • dJ221C16.5
    • DmeH1
    • H1
    • H1 0 histone
    • H1 histone family member 0
    • H1 histone family member 1
    • H1 histone family member 3
    • H1 histone family member 5
    • H1 histone family member N testis specific
    • H1 histone family member O oocyte specific
    • H1 histone family member X
    • H1(0)
    • H1.1
    • H1.2
    • H1.3
    • H1.4
    • H1.5
    • H10
    • H1A
    • H1f0
    • H1F0 protein
    • H1F1
    • H1F2
    • H1F3
    • H1F4
    • H1F5
    • H1FNT
    • H1FOO
    • H1FOO protein
    • H1FOO_HUMAN
    • H1FT
    • H1FV
    • H1FX
    • H1oo
    • H1t
    • H1T2
    • H1X
    • HANP1
    • His1
    • HisC
    • HIST1
    • HIST1H1A
    • HIST1H1B
    • HIST1H1C
    • HIST1H1D
    • HIST1H1E
    • HIST1H1T
    • Histone
    • Histone 1 H1a
    • Histone 1 H1b
    • Histone 1 H1c
    • Histone 1 H1d
    • Histone 1 H1e
    • Histone 1 H1t
    • Histone H1'
    • Histone H1.0
    • Histone H1.1
    • Histone H1.2
    • Histone H1.3
    • Histone H1.4
    • Histone H1.5
    • Histone H1oo
    • Histone H1x
    • MGC116819
    • MGC126630
    • MGC126632
    • MGC126642
    • MGC138176
    • MGC138345
    • MGC15959
    • MGC3992
    • MGC50807
    • MGC5241
    • MGC8350
    • Oocyte specific histone H1
    • Oocyte specific linker histone H1
    • Oocyte-specific histone H1
    • Oocyte-specific linker histone H1
    • osH1
    • Testicular H1 histone
    see all
  • FunctionMay play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
  • Tissue specificityOocyte-specific.
  • Sequence similaritiesBelongs to the histone H1/H5 family.
    Contains 1 H15 (linker histone H1/H5 globular) domain.
  • Cellular localizationCytoplasm. Nucleus. Chromosome.
  • Information by UniProt

Natural Cow Histone H1 protein images

  • SDS-PAGE showing ab89813 at approximately 31-33kDa.

References for Natural Cow Histone H1 protein (ab89813)

ab89813 has not yet been referenced specifically in any publications.

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