Natural Cow Osteocalcin protein (ab62262)

Overview

Description

  • NatureNatural
  • SourceNative
  • Amino Acid Sequence
    • SpeciesCow
    • Additional sequence informationSource = bovine bone

Specifications

Our Abpromise guarantee covers the use of ab62262 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Radioimmunoassay

    ELISA

    Dot blot

  • FormLiquid
  • Additional notesThe concentration of each lot may vary. For this product the concentration range is typically 5-10 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 7.40
    Constituents: 0.121% Tris, 50% Glycerol, 0.435% Sodium chloride

General Info

  • Alternative names
    • BGLAP
    • BGP
    • Bone gamma carboxyglutamate (gla) protein
    • Bone gamma carboxyglutamate gla protein osteocalcin
    • Bone gamma carboxyglutamate protein
    • Bone Gla protein
    • Gamma carboxyglutamic acid containing protein
    • Gamma-carboxyglutamic acid-containing protein
    • OC
    • OCN
    • OSTCN_HUMAN
    • Osteocalcin
    • OTTHUMP00000016586
    • PMF1
    see all
  • FunctionConstitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.
  • Sequence similaritiesBelongs to the osteocalcin/matrix Gla protein family.
    Contains 1 Gla (gamma-carboxy-glutamate) domain.
  • Post-translational
    modifications
    Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Natural Cow Osteocalcin protein (ab62262)

ab62262 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry and your interest in our products.

We purify the native Osteocalcinfrom bovine bone tissue. Therefore, we would expect all of the material to be carboxylated.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"