Overview

Description

  • NatureNatural
  • SourceNative
  • Amino Acid Sequence
    • AccessionF1MIZ7
    • SpeciesCow
    • Molecular weight60 kDa
    • Amino acids1 to 538
    • Additional sequence informationSource =bovine tissues

Specifications

Our Abpromise guarantee covers the use of ab125167 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

    SDS-PAGE

  • Purity> 60 % SDS-PAGE.
    Purity is greater than 60.0% as determined by SDS-PAGE.
  • FormLiquid
  • Additional notes


    Binds IgG-type human auto-antibodies.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.38% HEPES, 20% Glycerol, 2.34% Sodium chloride

General Info

  • Alternative names
    • 60 kDa ribonucleoprotein Ro
    • 60 kDa Ro protein
    • 60 kDa SS A/Ro ribonucleoprotein
    • 60 kDa SS-A/Ro ribonucleoprotein
    • Autoantigen Ro/SSA, 60-KD
    • bA101E13.2
    • Gastric cancer multi drug resistance protein
    • Ribonucleoprotein autoantigen SS A/Ro
    • RO 60
    • Ro 60 kDa autoantigen
    • RO60
    • RO60_HUMAN
    • RoRNP
    • Sjoegren syndrome antigen A2
    • Sjoegren syndrome type A antigen
    • Sjogren syndrome antigen A2
    • Sjogren syndrome antigen A2 (60kD ribonucleoprotein autoantigen SS A/Ro)
    • Sjogren syndrome antigen A2 (60kDa ribonucleoprotein autoantigen SS A/Ro)
    • SS A
    • SS-A
    • SS-A/Ro
    • SSA
    • SSA 2
    • SSA2
    • TROVE 2
    • TROVE domain family member 2
    • TROVE2
    see all
  • FunctionRNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation.
  • Sequence similaritiesBelongs to the Ro 60 kDa family.
    Contains 1 TROVE domain.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • Information by UniProt

References for Natural Cow TROVE2 protein (ab125167)

ab125167 has not yet been referenced specifically in any publications.

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