Overview

Description

  • NatureNatural
  • SourceNative
  • Amino Acid Sequence
    • SpeciesCow
    • Additional sequence informationSource = prepared from Type XIII bovine trypsin (bovine pancreas)

Associated products

Specifications

Our Abpromise guarantee covers the use of ab93263 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityActivity: 0 U/mg Trypsin Activity.
  • Applications

    SDS-PAGE

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 1mM HCl, 10mM Calcium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Alpha-trypsin chain 2
    • Anionic trypsinogen
    • Beta trypsin
    • Beta-trypsin
    • Brain trypsinogen
    • Cationic trypsinogen
    • Digestive zymogen
    • Mesotrypsin
    • Mesotrypsinogen
    • MGC111183
    • MGC120174
    • MGC120175
    • MGC149362
    • MTG
    • Nonfunctional trypsin 1
    • Pancreatic trypsinogen III
    • Protease Serine 1
    • Protease serine 1 (trypsin 1)
    • Protease serine 2
    • Protease serine 2 (trypsin 2)
    • Protease serine 2 preproprotein
    • Protease serine 3
    • Protease serine 3 (mesotrypsin)
    • Protease serine 4 (trypsin 4 brain)
    • Prss1
    • PRSS2
    • PRSS3
    • PRSS4
    • Serine protease 1
    • Serine protease 2
    • Serine protease 3
    • Serine protease 4
    • T9
    • TRP1
    • TRY1
    • TRY1_HUMAN
    • TRY2
    • TRY3
    • TRY4
    • TRY8
    • TRYP1
    • TRYP2
    • Trypsin 1
    • Trypsin 2
    • Trypsin 3
    • Trypsin I
    • Trypsin II
    • Trypsin III
    • Trypsin IV
    • Trypsinogen 1
    • Trypsinogen 2
    • Trypsinogen 4
    • Trypsinogen 5
    • Trypsinogen A
    • Trypsinogen, anionic
    • Trypsinogen, cationic
    • Ttrypsinogen IV
    see all
  • FunctionHas activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates.
  • Involvement in diseaseDefects in PRSS1 are a cause of hereditary pancreatitis (HPC) [MIM:167800]; also known as chronic pancreatitis (CP). HPC is an autosomal dominant disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks.
  • Sequence similaritiesBelongs to the peptidase S1 family.
    Contains 1 peptidase S1 domain.
  • Post-translational
    modifications
    Occurs in a single-chain form and a two-chain form, produced by proteolytic cleavage after Arg-122.
  • Cellular localizationSecreted > extracellular space.
  • Information by UniProt

Natural cow Trypsin protein images

  • 12% SDS-PAGE
    Lane 1: Trypsin (5 ug) Non-reduced
    Lane 2: Trypsin (5 ug) Reduced
    Lane 3: Prestained Standard

References for Natural cow Trypsin protein (ab93263)

ab93263 has not yet been referenced specifically in any publications.

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