Natural Human Alpha 2 Antiplasmin protein (ab81750)

Overview

Description

  • NatureNatural
  • SourceNative
  • Amino Acid Sequence
    • SpeciesHuman
    • Amino acids40 to 491

Specifications

Our Abpromise guarantee covers the use of ab81750 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 7.5mM Potassium chloride, 50mM Potassium phosphate, 0.075mM EDTA, pH 7.4

General Info

  • Alternative names
    • A2AP
    • A2AP_HUMAN
    • AAP
    • Alpha 2 antiplasmin
    • Alpha 2 antiplasmin pigment epithelium derived factor
    • Alpha 2 AP
    • ALPHA 2 PI
    • Alpha 2 plasmin inhibitor
    • Alpha 2 plasmin inhibitor deficiency
    • Alpha-2-antiplasmin
    • Alpha-2-AP
    • Alpha-2-PI
    • Alpha-2-plasmin inhibitor
    • Antiplasmin deficiency
    • API
    • Plasmin inhibitor deficiency
    • PLI
    • Serine (or cysteine) peptidase inhibitor, clade F, member 2
    • Serine (Or cysteine) peptidase inhibitor, clade F, member 2, isoform CRA_c
    • Serine (or cysteine) proteinase inhibitor, clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2
    • Serine (Or cysteine) proteinase inhibitor, clade F, member 2
    • Serine or cysteine peptidase inhibitor clade F member 2
    • Serpin F2
    • Serpin peptidase inhibitor clade F
    • Serpin peptidase inhibitor, clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2
    • SERPINF2
    see all
  • FunctionSerine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.
  • Tissue specificityExpressed by the liver and secreted in plasma.
  • Involvement in diseaseDefects in SERPINF2 are the cause of alpha-2-plasmin inhibitor deficiency (APLID) [MIM:262850]. APLID is an autosomal recessive disorder resulting in severe hemorrhagic diathesis.
  • Sequence similaritiesBelongs to the serpin family.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Natural Human Alpha 2 Antiplasmin protein (ab81750)

ab81750 has not yet been referenced specifically in any publications.

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