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Amino Acid Sequence
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein Determination: Extinction Coefficient (E) 0.1% at 280nm, 1cm pathway = 0.703. Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20ºC.
Constituents: 200mM Sodium chloride, 20mM Bis-Tris, pH 6.4
Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.
Expressed by the liver and secreted in plasma.
Involvement in disease
Defects in SERPINF2 are the cause of alpha-2-plasmin inhibitor deficiency (APLID) [MIM:262850]. APLID is an autosomal recessive disorder resulting in severe hemorrhagic diathesis.
Belongs to the serpin family.
Information by UniProt
Natural Human Alpha 2 Antiplasmin protein images
SDS-PAGE - Alpha 2 Antiplasmin protein (Human) (ab90921)
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