Natural Human Alpha Thrombin protein (ab81589)

Overview

Description

  • Nature
    Native
  • Source
    Native
  • Amino Acid Sequence
    • Species
      Human
    • Amino acids
      328 to 622

Specifications

Our Abpromise guarantee covers the use of ab81589 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Specific Activity: <1% Thrombin activity. Active site blocked by FPR- chloromethylketone.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Liquid
  • Additional notes

    The active site of thrombin is blocked with Phe-Pro-Arg chloromethylketon (CMK).

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20mM HEPES, 150mM Sodium chloride, pH 7.4

General Info

  • Alternative names
    • Coagulation factor II
    • Coagulation factor II (thrombin)
    • F2
    • prothrombin B-chain
    • PT
    • serine protease
    see all
  • Relevance
    Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
  • Cellular localization
    Secreted › extracellular space.

References for Natural Human Alpha Thrombin protein (ab81589)

ab81589 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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