Natural Human Alpha Thrombin protein (ab81589)

Overview

Description

  • NatureNatural
  • SourceNative
  • Amino Acid Sequence
    • SpeciesHuman
    • Amino acids328 to 622

Specifications

Our Abpromise guarantee covers the use of ab81589 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activitySpecific Activity: <1% Thrombin activity. Active site blocked by FPR- chloromethylketone.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Additional notes

    The active site of thrombin is blocked with Phe-Pro-Arg chloromethylketon (CMK).

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20mM HEPES, 150mM Sodium chloride, pH 7.4

General Info

  • Alternative names
    • Coagulation factor II
    • Coagulation factor II (thrombin)
    • F2
    • prothrombin B-chain
    • PT
    • serine protease
    see all
  • RelevanceThrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
  • Cellular localizationSecreted › extracellular space.

References for Natural Human Alpha Thrombin protein (ab81589)

ab81589 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"