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Amino Acid Sequence
Amino acids 328 to 622 Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activity Specific Activity: <1% Thrombin activity.
Active site blocked by FPR- chloromethylketone.
Purity > 95
The active site of thrombin is blocked with Phe-Pro-Arg chloromethylketon (CMK).
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 20mM HEPES, 150mM Sodium chloride, pH 7.4
Coagulation factor II
Coagulation factor II (thrombin)
Relevance Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
Cellular localization Secreted › extracellular space.
References for Natural Human Alpha Thrombin protein (ab81589)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"